Publications
We teach evidence synthesis because we practise it.
Peer-reviewed systematic reviews, scoping reviews, meta-analyses and primary studies by the Centicini team and our collaborators, in journals including BMC, Frontiers and Springer Nature titles.
50+
listed publications
2021–2026
years of peer-reviewed output
2026
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DOIMethods & frameworks
Innocent, D. C., Innocent, R. C., & Innocent, I. P. (2026). Framework for developing explainable artificial intelligence models for neglected tropical disease diagnosis in low-resource settings. Frontiers in digital health, 8, 1900500.
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DOISystematic review
Innocent, D. C., Anyakorah, P. E., Innocent, R. C., Dozie, I. N. S., Chukwuocha, U. M., & Emerole, C. O. (2026). Performance and clinical utility of image-based machine learning models for the diagnosis of neglected tropical diseases in low- and middle-income countries: a systematic review. BMC infectious diseases, 26(1), 1555.
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DOINarrative review
Innocent DC, Innocent RC and Innocent IP (2026) Explainable machine learning for predicting treatment outcomes in female genital schistosomiasis and HIV co-morbidity: a narrative review and translational framework. Front. Trop. Dis. 7:1894145.
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DOIPrimary research
Innocent, D. C., Anyakorah, P. E., Innocent, R. C., Innocent, I. P., Chukwuocha, U. M., Dozie, I. N. S., ... & Damileye, A. T. (2026). Explainable AI for differential diagnosis of skin-manifesting neglected tropical diseases (NTDS) in darker skin tones. BMC Artificial Intelligence, 2(1), 15.
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DOIMethods & frameworks
Innocent, D. C., Innocent, R. C., Anyakorah, P. E., Innocent, I. P., Chukwuemeka, P. S., Anuwe, J. C., Eugene, C. F., Udoh, O. U., Nwokeji, C. E., Emerole, C. O., Chukwuocha, U. M., & Dozie, I. N. S. (2026). Balancing rigor and pragmatism in health research: a guide to choosing study designs for real-world settings. BMC medical research methodology, 26(1), 149.
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DOIPrimary research
Anyakorah, P. E., Innocent, D. C., Ezenwa, C. J., Nwaokoro, J. C., & Emina, V. A. (2026). Knowledge and perception of hypertension among academic staff of Federal University of Technology Owerri, Imo State, Nigeria. Discover Public Health, 23(1), 402.
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DOISystematic review
Efe, J. J., Anibor, E., Pandey, P., Sunday, O. G., Innocent, D. C., Anyakorah, P. E., & Emmanuel, O. I. (2026). Blood-based biomarkers for early diagnosis of Alzheimer's disease: a current systematic review of diagnostic accuracy studies. BMC neurology, 26(1), 502.
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DOIScoping review
Innocent, D.C., Innocent, R.C. & Innocent, I.P. Machine learning models in clinical decision support systems: a scoping review. Bull Natl Res Cent 50, 115 (2026).
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DOIScoping review
Innocent, D. C., Anyakorah, P. E., Innocent, R. C., Anuwe, JC., Innocent, I. P & Gabson DJ. (2026). A scoping review of antimicrobial stewardship programmes in tertiary hospitals across low- and middle-income countries. Antimicrob Resist Infect Control (2026).
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DOISystematic review & meta-analysis
Innocent, D. C., Innocent, R. C., Anyakorah, P. E., Chukwuemeka, P. S., Eugene, C., Anuwe, J. C., Udoh, O. U., Nwachukwu, B. C., Obani, S. I., Dozie, I. N. S., Chukwuocha, U. M., Okwara, D. I., Moroh, J. E., George, T. C., Blessing, A. A., & Efe, J. J. (2026). Comparative effectiveness of ivermectin versus permethrin for the treatment of scabies: an updated systematic review and meta-analysis. BMC infectious diseases, 26(1), 1213.
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DOINarrative review
Anyakorah, P. E., Innocent, D. C., Chukwuemeka, P. S., Ezenwa, C. J., Nwaokoro, J. C., Emina, V. A., & Anuwe, J. C. (2026). A narrative review of epidemiology risk factors and health system responses to hypertension in low and middle income countries between 2015 and 2025. Discover Public Health, 23(1), 1392.
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DOIPrimary research
Innocent DC, Innocent IP and Innocent RC (2026) Diagnostic accuracy of machine-learning–based image analysis for early detection of Kaposi sarcoma in people living with HIV. Front. Artif. Intell. 9:1894174.
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DOIScoping review
Innocent, D. C., Akuana, C. M., Udoh, O. U., Innocent, R. C., Anyakorah, P. E., Innocent, I. P., Ekeleme, U. G., Chukwuocha, U. M., Dozie, I. N. S., Emerole, C. O., Anuwe, J. C., Nwegbu, F. C., Moroh, J. E., George, T. C., Blessing, A. A., Dozie, U. W., Osuoha, C. B., Ozaraebuka, G. A., & Efe, J. J. (2026). Climate-driven disruptions in local food systems and the transmission pathways of food-borne neglected tropical diseases in Sub-Saharan Africa: a scoping review. BMC public health, 26(1), 1482.
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DOIScoping review
Innocent DC, Innocent RC and Innocent IP (2026) Convolutional neural networks for medical imaging in resource-constrained settings: a scoping review of architectures, performance, and deployment challenges. Front. Artif. Intell. 9:1894126.
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DOISystematic review
Efe, J. O. J., Ochonogor, O. O., Lilian, C. O. E., Afokeoghene, U. J., Ikechukwu, O. E., Innocent, D. C., ... & Chidinma, A. (2026). A Systematic Review on Genetic Polymorphisms Associated with Hypertension Risk. Asian Journal of Medical Principles and Clinical Practice, 9(2), 1007-1025.
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ViewPrimary research
Ayalew, B. D., Umar, M., Tabasum, P., Qadri, M., Farooq, T., Getachew, E. Y., ... Innocent DC, Sharew, T. M. (2026). Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges. Food Safety and Health.
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DOISystematic review & meta-analysis
Innocent, D. C., Innocent, R. C., & Innocent, I. P. (2026). Impact of HIV infection on clinical presentation and diagnostic delay of skin neglected tropical diseases: a systematic review and meta-analysis. Frontiers in Tropical Diseases, 7, 1894176.
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DOISystematic review & meta-analysis
Innocent, D.C, Chijindum Innocent, R., & Praise Innocent, I. (2026). Machine learning models in predicting antimicrobial resistance in gonorrhea: a systematic review and meta-analysis. Frontiers in Public Health, 14, 1894150.
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Systematic review Accepted
Anyakorah, P. E., Innocent, D. C., Chukwuemeka, P. S., Ezenwa, C. J., Nwaokoro, J. C., & Emina, V. A. (2026). Effect of Physical Activity Interventions on Blood Pressure Control Among Adults with Hypertension in Africa: A Systematic Review. Sport Sciences for Health.
2025
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DOISystematic review
Anyakorah, P. E., Aguna, F. C., Innocent, D. C., Uwandu-Uzoma, A. C., Ekeleme, U. G., Obasi, C. C., Eneh, S. C., Ahunam, C. P., Dike, I. C., Maduekwe, V. C., Ayando, O. D., Duruji, C. O., Innocent, R. C., Uwaezuoke, P. C., Adenuga, O. O., & Emerole, C. O. (2025). A qualitative systematic review of umbilical cord care practices in Nigeria. BMC pediatrics, 25(1), 34.
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DOISystematic review & meta-analysis
Dozie, I. N. S., Chukwuocha, U. M., Innocent, D. C., Dozie, U. W., & Chukwuemeka, P. S. (2025). A systematic review and meta-analysis of the prevalence and risk factors of prostate cancer in Nigeria. BMC cancer, 25(1), 1932.
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DOIPrimary research
Onukansi, F. O., Anokwuru, C. C., Eneh, S. C., Odey, G. O., Onah, D. O., Sokunbi, T., Innocent, D. C., Dozie, U. W., Umoke, P. C., Ojo, T. O., & Ezejindu, C. N. (2025). Investing in traditional medicine: leveraging evidence and innovative research to strengthen the fight against malaria in Nigeria. Malaria journal, 24(1), 232.
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DOISystematic review
Nwaozuru, U., Murphy, P., Richard, A., Obiezu-Umeh, C., Shato, T., Obionu, I., Innocent DC ... & Iwelunmor, J. (2025). The sustainability of health interventions implemented in Africa: an updated systematic review on evidence and future research perspectives. Implementation Science Communications, 6(1), 39.
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ViewPrimary research
Beatrice, O. C., Njoku-Obi, T. N., Innocent, D. C., & Chika, I. V. (2025). Insights on Integrated Mobile Health Intervention on Socio-Demographic Characteristics in Relation to Medication Adherence. Journal homepage: com/gjrms, 5(03).
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Narrative review
Beatrice, O. C., Njoku-Obi, T. N., Chika, I. V., Dozie, U. W., & Innocent, D. C. (2025). Integrated Mobile Health Interventions On Cd4 Count Outcomes Among Hiv/Tb Co-Infected: An Impact Based Narrative Review. African Journal of Biology and Medical Research.
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Narrative review
Beatrice, Osuoha Chinyere, Treasure Njideka Njoku-Obi, David Chinaecherem Innocent, Igiri Vivian Chika, and Ugonma Winnie Dozie. "A narrative review of appointment and medication adherence in socio-demographic contexts." (2025). African Journal of Biology and Medical Research.
2024
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ViewPrimary research
Plernta Ethisan, Nawal Naeem, Abdul Jabbar Bhutto, Ayesha Khan, David Chinaecherem Innocent, Ramesh Kumar (2024). Factors Affecting the Quality of Life among the Aging Population during the Coronavirus Disease-19 Pandemic in Thailand. Journal of Dow university Health Sciences.
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Primary research
Dozie, U.W., Benjamin, W.I., Innocent, D.C., Anyanwu, E.C., Chukwuocha, U.M., Innocent, R.C., Dike, I.C., Akpevba, E., Rabaan, A.A. and Mary, O.O., (2024). Knowledge, acceptability and willingness to receive HPV vaccine among women in Owerri municipal Imo state. Academic Journal of Health Sciences: Medicina Balear, 39(2), pp.37-45.
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Systematic review
Innocent, D. C., Anyakorah, P. E., Obani, S. I., Innocent, R. C., Emerole, C. O., Uwaezuoke, A. C., ... & Duruji, C. O. (2024). Correlative Study on Body Mass Index and Blood Pressure in the United Kingdom: A Systematic Review.
2023
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DOIPrimary research
Moroh, J. E., Innocent, D. C., Chukwuocha, U. M., Vasavada, A., Kumar, R., Siddiq, M. A., Rais, M. A., Rabaan, A. A., Alshehri, W. M., Alharbi, A. M., Binateeq, M. A., Halwani, M. A., Al-Ahdal, T., Padhi, B. K., & Sah, R. (2023). Seasonal Variation and Geographical Distribution of COVID-19 across Nigeria (March 2020-July 2021). Vaccines, 11(2), 298.
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Primary research
Dozie, U.W., Ezeala, O.V., David, C. I., Dozie, K.C.N., Chukwuocha, U.M., Iwuala, C.C., Osuoji, N.J., Okoro, C.C., Chukwu, O.R., Eneh, S.C. and Dozie, I.N.S., 2023. Factors Associated with health seeking delay in the screening of cervical cancer among women in Imo state, south Eastern Nigeria. Cancer Treatment and Research Communications, p.100765.
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DOINarrative review
Eneh, S. C., Admad, S., Nazir, A., Onukansi, F. O., Oluwatobi, A., Innocent, D. C., & Ojo, T. O. (2023). Cholera outbreak in Syria amid humanitarian crisis: the epidemic threat, future health implications, and response strategy - a review. Frontiers in public health, 11, 1161936.
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ViewNarrative review
Rabaan, A. A., Alestad, J. H., Halwani, M. A., Innocent, D. C., & Garout, M. (2023). An overview of the SARS-COV-2 mutational profile in relation to variant of concerns (VOC): a narrative review. J Popul Ther Clin Pharm, 30(17), 112-132.
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ViewSystematic review
Egbujor, C. E., Innocent, D. C., Chukwuocha, U. M., Ekeleme, U. G., & Ekenze, J. C. (2023). The effectiveness of interventions for improving the uptake of Intermittent Preventive Treatment (IPT) for malaria control among pregnant women in sub-saharan Africa: A systematic literature review Arch Prev Med 8 (1): 008-019. doi. org/10.17352/apm, 32.
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ViewNarrative review
Rabaan, A. A., Alshahrani, F. S., Halwani, M. A., Nassar, M. S., Bakhrebah, M. A., Innocent DC & Abdulaal, W. H. (2023). A narrative review on SARS-CoV-2 infection in pediatrics: concerns, challenges, management, and mitigation strategies. J Popul Ther Clin Pharmacol, 30(17), 187-205.
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Systematic review
Innocent, D. C., Vasavada, A., Eneh, S. C., & Uwaezuoke, A. C. (2023). Systematic review evidence on the factors influencing teenage mothers utilization of maternal health services in Sub Saharan Africa. Academic Journal of Health Sciences, 38(2), 9-23.
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DOIPrimary research
Okorie O. M., Iwuoha G., Amadi A. N., Nwoke E. A., Okorie M. E., Ekeleme U. G., Iwuala C. C., Iwuagwu U. O., Innocent D. C., Njoku A. B., Akpevba E. (2023), The Usage of Personal Protective Equipment (PPE) Among Quarry Workers in Abia and Ebonyi State, South East, Nigeria. African Journal of Biology and Medical Research, 6(3), 56-62. 83UIVVA1.
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DOIPrimary research
Akanno, F. C., Obasi, C. C., Chukwuocha, U. M., Dozie, U. W., Ori, C. L. U., Sule, G. I. O., ... & Innocent, D. C. (2023). Survival Times of Breast Cancer Patients In Nigeria: Application of Cox and Parametric Survival Models. African Journal of Biology and Medical Research.
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Primary research
Innocent DC, Agwu UF, Uzowuihe PN, Ezejindu CN, Innocent RC, Uwaezuoke AC, Unegbu VN, Vasavada A & Andani R (2023) Assessment of Long Lasting Insecticide Treated Net among Women of Child Bearing Age in a Community in South Eastern Nigeria.
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ViewNarrative review
Gerald Walter Ugodi, Rejoicing Chijindu Innocent, Fredrick C. Asogwa, DC Innocent (2023) In Vitro Anti-Inflammatory Models Used In Bioactivity Study Of Crude Herbal Extract; An Evaluative Review European journal of pharmaceutical sciences: official journal of the European Federation for Pharmaceutical Sciences.
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DOISystematic review & meta-analysis
Innocent, D. C., Innocent, R. C., Kumar, R., Rabaan, A. A., Emerole, C. O., Ayando, O. D., Dike, I. C., & Duruji, C. O. (2023). A systematic review and meta-analysis on the effect of curcumin (turmeric) on fasting blood glucose and glycated haemoglobin in patients with type 2 diabetes mellitus. medRxiv.
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Primary research
Anyanwu, E. C., Ogbonna, P. C., & Innocent, D. C. (2023). Exploring the awareness level of cervical cancer concept among post-menopausal women in Ezinihitte Mbaise, Imo State, Nigeria. Iconic Research and Engineering Journals, 7(4), 187-193.
2022
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DOIPrimary research
Innocent, D. C., Emerole, C., Ezejindu, C. , Dozie, U. , Obani, S. , Uwandu-Uzoma, A. , Nwaokoro, C. , Udeh, M. , Eneh, S. , Uwaezuoke, A. , Iwuji, K. , Udoewah, S. , Uzowuihe, P. and Maduekwe, V. (2022) Examination of Common Occupational Hazards among Healthcare Workers in a University Healthcare Center in Southeastern Nigeria. Health, 14, 833-852.
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Dozie, U.W., Agoha, M. C., Innocent, D. C., Dozie, I. C. N., Chukwuocha, U. M., Chukwu, R. O., Osuoji, J. N., Uzowuihe, P. N., and Dozie, I. N. S. (2022) Exploring the Knowledge, Perception and Uptake of Prostate Cancer Screening among Men Aged 40 Years and above in Owerri West, Imo State, South Eastern Nigeria, Discoveries in Public Health, Volume 1 June, 2022 - pp 77-90.
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ViewSystematic review & meta-analysis
Innocent, D. C., Vasavada, A. and Ezejindu, C, N. (2022) A Systematic Review and Meta-Analysis on the Efficacy and Safety of Combination Therapy with Sodium-Glucose Cotransporter Type 2 Inhibitor (SGLT2I) and dipeptidase-4 Inhibitor (DPP4I) in treatment of type 2 diabetes. International Journal of Research and Review, ISSN: 2349-9788.
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Ofoelo, E.C., Innocent, D.C., Vasavada, A. and Ofoelo, I. L. (2022) Prevalence of adverse drug effects of anti-retroviral drugs on HIV-positive patients who are receiving anti-retroviral treatment in general hospital Onitsha, Anambra, Nigeria. Academic Journal of Health Sciences.
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Primary research
Uchechukwu Olive Iwuagwu, Agwu Nkwa Amadi, Blessed Okwuchi Nworuh, Chimezie C. Christian Iwuala, David Chinaecherem, Innocent, Michael Okwudiri Ikeanumba, and Mary Onyinyechi Okorie. (2023) "Assessment of The Bacteriological Qualities of Meat and Contact Surfaces in Markets in Abia State, Nigeria." Journal of Clinical Mircobiology and Biotechnology: 2023-10.
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David Chinaecherem Innocent, Ugochukwu Fortune Agwu, Promise Nwanyinma Uzowuihe, Cosmas Nnadozie Ezejindu, Rejoicing Chijindum Innocent, & Angelica Chinecherem Uwaezuoke. (2023). Knowledge and Practice of Breast Cancer Screening among Women in Enugu South, Nigeria. Global Journal of Medical Research, 23(F1), 11–26.
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Nwaokoro, C. J., Innocent, D. C., Ezejindu, C. N., Vasavada, A. and Eneh, S.C. (2022) Assessment of Hypertension Knowledge Among Adults Living In Owerri Metropolises. International Journal of Research and Scientific Innovation, Vol IX ISSN:2321-2705.
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ViewSystematic review & meta-analysis
Innocent, D. C., Vasavada, A., Uwaezuoke, A. C., Uwaezuoke, P. C., & Innocent, R. C. (2022). Metformin versus Glyburide in the management of gestational diabetes: a systematic review and meta-analysis. International Journal of Research and Review.
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Innocent, D. C., Ezejindu, C. N., Vasavada, A., & Duruji, C. O. (2022). Awareness, knowledge and attitude of undergraduates towards sickle cell disease in South Eastern Nigeria. International Journal of Research and Scientific Innovation, IX.
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Innocent, D. C., Afor, J. I., Ezejindu, C. N., Nwaokoro, C. J., Obani, S. I., Eneh, S. C., Uwaezuoke, A. C., Vasavada, A., Adiaetok, U. S., & Uzonwuihe, P. N. (2022). Evaluation of the bacteriological quality of sachet and bottled water consumed in a south-eastern university in Nigeria. IRE Journals, 6(1).
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Innocent, D. C., Obani, S., Ezejindu, C. N., Uwaezuoke, A. C., & Vasavada, A. (2022). Personal hygiene practices among selected secondary schools at South Eastern Nigeria. International Journal of Research and Scientific Innovation, IX.
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DOIPrimary research
Ezejindu, C. N., Onyemachi, P. E., Innocent, D. C., Uwandu-Uzoma, A. C., Eneh, S. C., Adebayo, I. A., Uwaezuoke, A. C., & Okoroh, A. P. (2022). Epidemiological study on breast cancer-associated risk factors and screening practices among women in Mbaise, Imo State, Nigeria. International Journal of Innovative Research in Science Engineering and Technology, 7(6).
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Innocent, D. C., Ezejindu, C. N., Onyemachi, P. E., Eneh, S. C., Nazir, H., Uwandu-Uzoma, A. C., & Okoroh, A. P. (2022). Assessment of family planning among Abia State University undergraduate students. IRE Journals, 5(12).
2021
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Primary research
Dozie, Ugonma., Ibe, S., Nwaokoro, C., Chukwuocha, U., Udujih, O., Innocent, DC., & Onyewu, N. (2021). Compliance with Covid-19 Non-Medicinal Preventive Protocol and Intent to Accept Covid-19 Vaccine Among Adults in South Eastern Nigeria., EuropePMC.
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